The use of an ultra pure, ultra inert silica has many recognized benefits including improved reproducibility, lifetime and chromatographic performance (particularly with basic molecules). However, since the ultra inert silica surface effectively no longer contributes to the separation, C18 columns manufactured with high purity silicas show near identical selectivity. It is therefore highly likely that a problem separation on one leading brand will not be significantly improved by changing to an alternate manufacturer?s equivalent product.
For many years, experienced chromatographers have been seeking phases with the proven performance and reproducibility benefits shown by such leading C18 column brands, but which additionally provide the alternate selectivity required for their challenging applications.
ACE C18-PFP is a unique C18 bonded HPLC column with the extra selectivity of a pentafluorophenyl (PFP) phase.